Which condition results in smooth, white patches of skin due to the loss of melanocytes?

The condition characterized by smooth, white patches of skin resulting from the loss of melanocytes is indeed vitiligo. This skin disorder occurs when the cells responsible for producing melanin, which gives skin its color, are destroyed or stop functioning. As a result, areas of the skin lose their pigment and become noticeably lighter than the surrounding skin.

Vitiligo can affect any part of the body, and the patches typically have distinct edges. Unlike some other skin conditions, such as seborrheic dermatitis or psoriasis, which involve inflammation, scaling, or other symptoms, the hallmark of vitiligo is the lack of color in the affected areas, making it unique in its presentation. Additionally, neurodermatitis is usually associated with intense itching and scratching rather than changes in skin pigmentation. Thus, vitiligo stands out as the correct answer due to its specific association with melanocyte loss and the resulting depigmentation.